Women Live Longer Than Men. But Men, You Live Healthier.

It's probably something you've always wondered.  Why do women live longer than men? Maybe not.

And the answer is, no one knows!  When I was a kid, it was thought because most women didn't work (outside the home, that is!). They stayed home and baked brownies and took the kids to the park and the playground and looked pretty and fetching when Dad came home.  Well, some moms did.  (Not mine.)

But a new study says that women do live longer than men, and their bonus lifespan is the same in mammals and some birds and primates and just about any living (human) thing walking around on the earth.

"Humans are the only species in which one sex is known to have a ubiquitous survival advantage,” the UAB researchers write in their research review covering a multitude of species, according to newswise.com. “Indeed, the sex difference in longevity may be one of the most robust features of human biology.”

Though other species, from roundworms and fruit flies to a spectrum of mammals, show lifespan differences that may favor one sex in certain studies, contradictory studies with different diets, mating patterns or environmental conditions often flip that advantage to the other sex. With humans, however, it appears to be all females all the time.

“We don’t know why women live longer,” says Steven Austad, Ph.D., of the University of Alabama at Birmingham, distinguished professor and chair of the UAB Department of Biology in the UAB College of Arts and Sciences. “It’s amazing that it hasn’t become a stronger focus of research in human biology.”

Newswise.com reports that evidence of the longer lifespans for women includes:

• The Human Mortality Database, which has complete lifespan tables for men and women from 38 countries that go back as far as 1751 for Sweden and 1816 for France. “Given this high data quality, it is impressive that for all 38 countries for every year in the database, female life expectancy at birth exceeds male life expectancy,” write Austad and and Kathleen Fischer, Ph.D., a research assistant professor of biology.

• A lifelong advantage. Longer female survival expectancy is seen across the lifespan, at early life (birth to 5 years old) and at age 50. It is also seen at the end of life, where Gerontology Research Group data for the oldest of the old show that women make up 90 percent of the supercentenarians, those who live to 110 years of age or longer.

• The birth cohorts from the mid-1800s to the early 1900s for Iceland. This small, genetically homogenous country — which was beset by catastrophes such as famine, flooding, volcanic eruptions and disease epidemics — provides a particularly vivid example of female survival, Austad and Fischer say. Over that time, “life expectancy at birth fell to as low as 21 years during catastrophes and rose to as high as 69 years during good times,” they write. “Yet in every year, regardless of food availability or pestilence, women at the beginning of life and near its end survived better than men.”

• Resistance to most of the major causes of death. “Of the 15 top causes of death in the United States in 2013, women died at a lower age-adjusted rate of 13 of them, including all of the top six causes,” they write. “For one cause, stroke, there was no sex bias, and for one other, Alzheimer’s disease, women were more at risk.”

So I guess we don't have it all, after all. 

Differences may be due to hormones, perhaps as early as the surge in testosterone during male sexual differentiation in the uterus. Longevity may also relate to immune system differences, responses to oxidative stress, mitochondrial fitness or even the fact that men have one X chromosome (and one Y), while women have two X chromosomes.

But here's a twist.

“One of the most puzzling aspects of human sex difference biology,” write Austad and Fischer, “something that has no known equivalent in other species, is that for all their robustness relative to men in terms of survival, women on average appear to be in poorer health than men through adult life.”

Hmm.  

This higher prevalence of physical limitations in later life is seen not only in Western societies, they say, but also for women in Bangladesh, China, Egypt, Guatemala, India, Indonesia, Jamaica, Malaysia, Mexico, the Philippines, Thailand and Tunisia.

One intriguing explanation for this mortality-morbidity paradox is a possible connection with health problems that appear in later life. Women are more prone to joint and bone problems, such as osteoarthritis, osteoporosis and back pain, than are men. Back and joint pain tends to be more severe in women, and this could mean chronic sleep deprivation and stress. Thus, the sex differences in morbidity could be due to connective tissue maladies in women, and connective tissue in humans is known to respond to female sex hormones.










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