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Showing posts with the label topoisomerases

Prevent Autism? It Just May Be -- And Yes, It's the Environment

Could it possibly be true?  Could they have found a cause for autism? A new study could have important implications for ASD detection and prevention. A new study says so.  According to newswise.com, "Problems with a key group of enzymes called topoisomerases can have profound effects on the genetic machinery behind brain development and potentially lead to autism spectrum disorder (ASD)." The Web site attributed the significant advance in the hunt for environmental factors behind autism to scientists at the University of North Carolina School of Medicine, who made this finding which lends new insights into the disorder’s genetic causes. "Our study shows the magnitude of what can happen if topoisomerases are impaired,” said senior study author Mark Zylka, PhD, associate professor in the Neuroscience Center and the Department of Cell Biology and Physiology at UNC. “Inhibiting these enzymes has the potential to profoundly affect neurodevelopment — perhaps even more so